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of voluntary but not limbically in uenced automatic respiration Arch Neurol 48:1190, 1991 NATHAN PW, SMITH MC: The location of descending bers to sympathetic neurons supplying the eye and sudomotor neurons supplying the head and neck J Neurol Neurosurg Psychiatry 49:187, 1986 NEWSOM DAVIS J: An experimental study of hiccup Brain 39:851, 1970 ONUFROWICZ B: On the arrangement and function of cell groups of the sacral region of the spinal cord of man Arch Neurol Psychopathol 3: 387, 1900 OPPENHEIMER D: Neuropathology of autonomic failure, in Bannister R (ed): Autonomic Failure, 2nd ed New York, Oxford University Press, 1988, chap 25, pp 451 463 PASZTOR A, PASZTOR E: Spinal vasomotor re ex and Cushing response Acta Neurochir 52:85, 1980 PENFIELD W, JASPER H: Epilepsy and the Functional Anatomy of the Human Brain Boston, Little, Brown, 1954, p 414 PETITO CK, BLACK IB: Ultrastructure and biochemistry of sympathetic ganglia in idiopathic orthostatic hypotension Ann Neurol 4:6, 1978 PHILLIPS JR, ELDRIDGE FL: Respiratory myoclonus (Leeuwenhoek s disease) N Engl J Med 289:1390, 1973 PICK J: The Autonomic Nervous System Philadelphia, Lippincott, 1970 PLUM F: Cerebral lymphoma and central hyperventilation Arch Neurol 47: 10, 1990 POLINSKY RJ: Neuropharmacological investigation of autonomic failure, in Mathias CJ, Bannister R (eds): Autonomic Failure: A Textbook of Clinical Disorders of the Autonomic Nervous System, 4th ed New York, Oxford University Press, 1999, pp 334 358 POLINSKY RJ, KOPIN IJ, EBERT MH, WEISE V: Pharmacologic distinction of different orthostatic hypotension syndromes Neurology 31:1, 1981 POLKEY MI, LYALL RA, MOXHAM J, LEIGH PN: Respiratory aspects of neurological disease J Neurol Neurosurg Psychiatry 66:5, 1999 PORTER JM, RIVERS SP, ANDERSON CS, BAUR GM: Evaluation and management of patients with Raynaud s syndrome Am J Surg 142:183, 1981 RAJPUT AH, ROZDILSKY B: Dysautonomia in parkinsonism: A clinicopathologic study J Neurol Neurosurg Psychiatry 39:1092, 1976 RHODES RH, WIGHTMAN HR: Nucleus of the tractus solitarius metastasis: Relationships to respiratory arrest Can J Neurol Sci 27:328, 2000 ROBINSON B, JOHNSON R, ABERNETHY D, HOLLOWAY L: Familial distal dysautonomia J Neurol Neurosurg Psychiatry 52:1281, 1989 ROPPER AH: Acute autonomic emergencies and autonomic storm, in Low PA (ed): Clinical Autonomic Disorders, 2nd ed Boston, Little Brown, 1997, chap 5, pp 791 801 ROPPER AH, WIJDICKS WFM, TRUAX BT: Guillain-Barre Syndrome Philadelphia, Davis, 1991, pp 109 112 RUCH T: The urinary bladder, in Ruch TC, Patton HD (eds): Physiology and Biophysics Vol 2: Circulation, Respiration, and Fluid Balance Philadelphia, Saunders, 1974, pp 525 546 SAKAKIBARA R, HATTORI T, YASUDA K, et al: Micturitional disturbance and the pontine tegmental lesion: Urodynamic and MRI analyses of vascular cases J Neurol Sci 141:105, 1996 SAMUELS MA: Cardiopulmonary aspects of acute neurologic disease, in Ropper AH (ed): Neurological and Neurosurgical Intensive Care, 3rd ed New York, Raven Press, 1993, pp 103 120 SCHOBEL HP, FISCHER T, HEUSZER K, et al: Preeclampsia A state of sympathetic overactivity N Engl J Med 335:1480, 1996 SCHUSTER MM: Clinical signi cance of motor disturbances of the enterocolonic segment Am J Dig Dis 11:320, 1966 SELYE H: The general adaptation syndrome and the diseases of adaptation J Clin Endocrinol Metab 6:117, 1946 SHANNON DC, MARSLAND DW, GOULD JB, et al: Central hypoventilation during quiet sleep in two infants Pediatrics 57:342, 1976 SHY GM, DRAGER GA: A neurological syndrome associated with orthostatic hypotension: A clinical-pathologic study Arch Neurol 2:511, 1960 SPOKES EGS, BANNISTER R, OPPENHEIMER DR: Multiple system atrophy with autonomic failure J Neurol Sci 43:59, 1979.

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TANSEY EM: Chemical neurotransmission in the autonomic nervous system: Sir Henry Dale and acetylcholine Clin Auton Res 1:63, 1991 THOMPSON PD, MELMON KL: Clinical assessment of autonomic function Anesthesiology 29:724, 1968 VERNINO S, LOW PA, FEALEY RD, et al: Autoantibodies to ganglionic acetylcholine receptors in autoimmune autonomic neuropathies N Engl J Med 343:847, 2000 WEISS HD: The physiology of human penile erection Ann Intern Med 76: 792, 1972

Before we can begin with the speci cs of trading interest-rate options, we need to make sure we have a basic background in the underlying instruments Interest-rate products are based on some type of bond, cash deposit, or loan rate We ll focus mostly on the bond aspect as related to US Treasury securities as the primary instruments for interest-rate trading and hedging A bond is a term debt obligation to the issuer backed by the assets and/or revenue of the issuer US Treasuries are backed by the full faith and credit of the United States and the revenue stream from US taxpayers Through the years US Treasuries have maintained one of the highest credit ratings in the world However, recently there is a bit more risk associated with the skyrocketing US national de cit, but the credit rating of US Treasuries is not expected to move off AAA any time soon US Treasuries come in several varieties: US Treasury bill The Treasury bill, or T-bill, is a zero coupon bond issued for terms of one month to one year The T-bill is considered to be the safest US Treasury security because of the short term T-bills are sold at auction by the Treasury Department and are usually purchased by institutions or governments Most individuals purchasing T-bills are doing so in the secondary market that is, purchasing them from an institution although recently the US Treasury has made T-bills available directly to the public Since these bonds have no coupon interest rate, they are sold at a discount at their face value The appreciation between the discount price and the par value or face value

WIGLEY FM: Raynaud s phenomenon N Engl J Med 347:1001, 2002 WILES CM: Neurogenic dysphagia J Neurol Neurosurg Psychiatry 54: 1037, 1991 YOUNG RR, ASBURY AK, CORBETT JL, ADAMS RD: Pure pan-dysautonomia with recovery: Description and discussion of diagnostic criteria Brain 98:613, 1975 ZIEGLER MG, LAKE R, KOPIN IJ: The sympathetic nervous system defect in primary orthostatic hypotension N Engl J Med 296:293, 1977

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